Literature summary extracted from

Park, K.; Mera, P.E.; Moore, T.C.; Escalante-Semerena, J.C.; Brunold, T.C.
Unprecedented mechanism employed by the Salmonella enterica EutT ATP Co(I)rrinoid adenosyltransferase precludes adenosylation of incomplete co(II)rrinoids (2015), Angew. Chem. Int. Ed. Engl., 54, 7158-7161 .

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.154	Salmonella enterica subsp. enterica serovar Typhimurium	Q9ZFV4	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.5.1.154	EutT	-	Salmonella enterica subsp. enterica serovar Typhimurium

General Information

EC Number	General Information	Comment	Organism
2.5.1.154	metabolism	EutT converts cob(II)alamin to an effectively four-coordinate Co(II) species so as to facilitate Co(II) to Co(I) reduction. The mechanism for bond dissociation involves binding of the nucleotide loop of Co(II)Cbl to a site remote from the Co(II) center. EutT fails to promote axial ligand dissociation for the substrate analogue cob(II)inamide, a natural precursor of cob(II)alamin. EutT can adenosylate complete and incomplete Co(I)rrinoids	Salmonella enterica subsp. enterica serovar Typhimurium

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Release 2023.1 (January 2023)