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Literature summary extracted from

  • Nemeti, B.; Csanaky, I.; Gregus, Z.
    Effect of an inactivator of glyceraldehyde-3-phosphate dehydrogenase, a fortuitous arsenate reductase, on disposition of arsenate in rats (2006), Toxicol. Sci., 90, 49-60 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.107 (S)-alpha-cholorhydrin 100 or 200 mg/kg (S)-alpha-cholorhydrin inhibits arsenate reduction by the liver, but not by the whole body Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.107 cytosol
-
 Rattus norvegicus 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.107 D-glyceraldehyde 3-phosphate + arsenate + NAD+ Rattus norvegicus
-
 1-arsono-3-phospho-D-glycerate + NADH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.107 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.107 heart
-
 Rattus norvegicus
-
1.2.1.107 kidney
-
 Rattus norvegicus
-
1.2.1.107 liver
-
 Rattus norvegicus
-
1.2.1.107 muscle
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.107 D-glyceraldehyde 3-phosphate + arsenate + NAD+
-
 Rattus norvegicus 1-arsono-3-phospho-D-glycerate + NADH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.107 AsV reductase
-
 Rattus norvegicus
1.2.1.107 GAPDH
-
 Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.107 NAD+
-
 Rattus norvegicus