Literature summary extracted from

McClory, J.; Timson, D.J.; Singh, W.; Zhang, J.; Huang, M.
Reaction mechanism of isopentenyl phosphate kinase A QM/MM study (2017), J. Phys. Chem. B, 121, 11062-11071 .

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.7.4.26	catalytically competent structure in complex with Mg2+ . Substrate binding results in significant conformational change of residues Lys204, Glu207, and Lys211 located on the alphaG helix to form a strong salt bridge network with Asp145, which in turn tethers the invariant Ser142 via H-bond interaction. The conformational change shuts the subtrate entrance channel formed between the alphaG and alphaE helices	Thermoplasma acidophilum

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.4.26	Thermoplasma acidophilum	Q9HLX1	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.4.26	Ta0103	-	Thermoplasma acidophilum

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Release 2023.1 (January 2023)