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Literature summary extracted from

  • Biswas, A.; Boutaghou, M.; Alvey, R.; Kronfel, C.; Cole, R.; Bryant, D.; Schluchter, W.
    Characterization of the activities of the CpeY, CpeZ, and CpeS bilin lyases in phycoerythrin biosynthesis in Fremyella diplosiphon strain UTEX 481 (2011), J. Biol. Chem., 286, 35509-35521 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.4.1.39 expression in Escherichia coli Microchaete diplosiphon

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.4.1.39 apo-[C-phycoerythrin alpha-subunit CpeA] + (3E)-phycoerythrobilin Microchaete diplosiphon
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 [C-phycoerythrin alpha-subunit CpeA]-Cys82-phycoerythrobilin
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 ?

Organism

EC Number Organism UniProt Comment Textmining
4.4.1.39 Microchaete diplosiphon Q6GZK3
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-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.4.1.39 apo-[C-phycoerythrin alpha-subunit CpeA] + (3E)-phycoerythrobilin
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 Microchaete diplosiphon [C-phycoerythrin alpha-subunit CpeA]-Cys82-phycoerythrobilin
-
 ?

General Information

EC Number General Information Comment Organism
4.4.1.39 physiological function CpeY is involved in biosynthesis of red-colored protein phycoerythrin. Subunit CpeY alone, but not CpeZ, can ligate phycoerythrobilin chromophores to phycoerythrin subunit CpeA, but the yield of CpeA-phycoerythrobilin is lower than achieved with subunits CpeY and CpeZ together. CpeY/CpeZ attach phycoerythrobilin at Cys82 of CpeA Microchaete diplosiphon