Literature summary extracted from

Nishihara, R.; Kobayashi, K.; Imae, R.; Tsumoto, H.; Manya, H.; Mizuno, M.; Kanagawa, M.; Endo, T.; Toda, T.
Cell endogenous activities of fukutin and FKRP coexist with the ribitol xylosyltransferase, TMEM5 (2018), Biochem. Biophys. Res. Commun., 497, 1025-1030 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.4.2.61	expressed in HEK-293 cells	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.4.2.61	UDP-alpha-D-xylose + 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein]	Homo sapiens	-	UDP + 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein]	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.2.61	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.2.61	UDP-alpha-D-xylose + 3-O-[Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein]	-	Homo sapiens	UDP + 3-O-[beta-D-Xyl-(1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-O-6-P-alpha-D-Man]-Ser/Thr-[protein]	-	?
2.4.2.61	UDP-alpha-D-xylose + Rib-ol-P-Rib-ol-P-phospho-CoreM3 peptide	-	Homo sapiens	UDP + ?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.4.2.61	ribitol xylosyltransferase	-	Homo sapiens
2.4.2.61	RXYL1	-	Homo sapiens
2.4.2.61	TMEM5	-	Homo sapiens
2.4.2.61	transmembrane protein 5	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
2.4.2.61	malfunction	enzyme defects cause Walker-Warburg syndrome	Homo sapiens

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Release 2023.1 (January 2023)