Literature summary extracted from

Nakano, M.; Ondo, K.; Takemoto, S.; Fukami, T.; Nakajima, M.
Methylation of adenosine at the N6 position post-transcriptionally regulates hepatic P450s expression (2020), Biochem. Pharmacol., 171, 113697 .

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.348	Homo sapiens	Q86U44 and Q9HCE5	Q86U44: METTL3, N6-adenosine-methyltransferase 70 kDa subunit. Q9HCE5: METTL14, N6-adenosine-methyltransferase non-catalytic subunit	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.348	Huh-7 cell	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.348	methyltransferase like 3	-	Homo sapiens
2.1.1.348	METTL3	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
2.1.1.348	physiological function	methylation of adenosine at the N6 position by methyltransferase like 3 (METTL3)-METTL14 complex post-transcriptionally regulates hepatic P450s expression	Homo sapiens

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Release 2023.1 (January 2023)