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Literature summary extracted from

  • Byeon, Y.; Back, K.
    Melatonin production in Escherichia coli by dual expression of serotonin N-acetyltransferase and caffeic acid O-methyltransferase (2016), Appl. Microbiol. Biotechnol., 100, 6683-6691 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.1.1.4 synthesis recombinant Escherichia coli expressing sheep serotonin N-acetyltransferase with rice caffeic acid O-methyltransferase produces 1.46 mg/L of melatonin in a culture medium, in response to 1 mM serotonin Oryza sativa Japonica Group
2.3.1.87 synthesis recombinant Escherichia coli that expresses sheep SNAT with rice caffeic acid O-methyltransferase produces up to 1.46 mg/l meatonin in culture medium in response to 1 mM serotonin Ovis aries

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.1.68 expressed in Escherichia coli BL21(DE3) cells Oryza sativa Japonica Group

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.4 Oryza sativa Japonica Group Q6ZD89 cf. EC 2.1.1.42
-
2.1.1.68 Oryza sativa Japonica Group Q6ZD89
-
-
2.3.1.87 Ovis aries Q29495
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.4 S-adenosyl-L-methionine + N-acetylserotonin
-
 Oryza sativa Japonica Group S-adenosyl-L-homocysteine + melatonin
-
 ?
2.1.1.68 S-adenosyl-L-methionine + N-acetylserotonin
-
 Oryza sativa Japonica Group S-adenosyl-L-homocysteine + melatonin
-
 ?
2.1.1.68 S-adenosyl-L-methionine + serotonin
-
 Oryza sativa Japonica Group S-adenosyl-L-homocysteine + 5-methoxytryptamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.4 COMT
-
 Oryza sativa Japonica Group
2.1.1.68 caffeic acid O-methyltransferase
-
 Oryza sativa Japonica Group
2.1.1.68 COMT
-
 Oryza sativa Japonica Group