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Literature summary extracted from
- Alkaline ceramidase mediates the oxidative stress response in Drosophila melanogaster through sphingosine (2019), J. Insect Sci., 19, 13 .
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.5.1.23 | additional information | generation of a Dacer-deficient Drosophila melanogaster mutant, which has higher catalase (CAT) activity and CAT transcription level, leading to higher resistance to oxidative stress induced by paraquat, quantitative proteomic analysis of wild-type and mutant cells. Three oxidoreductases, including two cytochrome P450 (CG3050, CG9438) and an oxoglutarate/iron-dependent dioxygenase (CG17807), are most significantly upregulated in the Dacer overexpressing mutant. Altered antioxidative activity in Dacer mutant might be responsible for increased oxidative stress resistance | Drosophila melanogaster |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.1.23 | Drosophila melanogaster | M9PDG7 | - |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.5.1.23 | alkaline ceramidase | - |
Drosophila melanogaster |
| 3.5.1.23 | bwa | - |
Drosophila melanogaster |
| 3.5.1.23 | Dacer | - |
Drosophila melanogaster |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 3.5.1.23 | malfunction | a Dacer-deficient Drosophila melanogaster mutant has higher catalase (CAT) activity and CAT transcription level, leading to higher resistance to oxidative stress induced by paraquat. Altered antioxidative activity in Dacer mutant might be responsible for increased oxidative stress resistance. Quantitative proteomic analysis of wild-type and mutant cells. Three oxidoreductases, including two cytochrome P450 (CG3050, CG9438) and an oxoglutarate/iron-dependent dioxygenase (CG17807), are most significantly upregulated in the Dacer overexpressing mutant | Drosophila melanogaster |
| 3.5.1.23 | physiological function | enzyme Dacer regulates expression of oxidative stress proteins | Drosophila melanogaster |
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Release 2023.1 (January 2023)
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