EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.295 | expressed in Escherichia coli HB101 cells | Mycobacterium tuberculosis |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.295 | 430000 | - |
gel filtration | Mycobacterium tuberculosis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.295 | a medium-chain acyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ | Mycobacterium tuberculosis | - |
a mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O | - |
? | |
2.3.1.295 | a medium-chain acyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ | Mycobacterium tuberculosis H37Rv | - |
a mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.295 | Mycobacterium tuberculosis | - |
- |
- |
2.3.1.295 | Mycobacterium tuberculosis H37Rv | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.295 | a medium-chain acyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ | - |
Mycobacterium tuberculosis | a mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O | - |
? | |
2.3.1.295 | a medium-chain acyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ | - |
Mycobacterium tuberculosis H37Rv | a mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.295 | pks12 | - |
Mycobacterium tuberculosis |
EC Number | General Information | Comment | Organism |
---|---|---|---|
2.3.1.295 | metabolism | the enzyme is necessary for antigen production, but did not affect synthesis of true isoprenols | Mycobacterium tuberculosis |