EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.14.18.10 | Iron | non-heme iron-requiring enzyme | Aspergillus fumigatus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.18.10 | Aspergillus fumigatus | - |
- |
- |
1.14.18.10 | Aspergillus fumigatus CEA17 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.18.10 | 4-methyl fecosterol + 6 ferricytochrome b5 + 3 O2 + 6 H+ | i.e. 4,24-dimethyl-cholesta-8,24(28)-dien-3beta-ol | Aspergillus fumigatus | 4,4-dimethyl fecosterol + 6 ferrocytochrome b5 + 4 H2O | - |
? | |
1.14.18.10 | 4-methyl fecosterol + 6 ferricytochrome b5 + 3 O2 + 6 H+ | i.e. 4,24-dimethyl-cholesta-8,24(28)-dien-3beta-ol | Aspergillus fumigatus CEA17 | 4,4-dimethyl fecosterol + 6 ferrocytochrome b5 + 4 H2O | - |
? | |
1.14.18.10 | parkeol + 6 ferricytochrome b5 + 3 O2 + 6 H+ | i.e. 4,4,14-trimethyl-cholesta-9(11),24-dien-3beta-ol | Aspergillus fumigatus | 9(11)-dehydroergosterol + 6 ferrocytochrome b5 + 4 H2O | - |
? | |
1.14.18.10 | parkeol + 6 ferricytochrome b5 + 3 O2 + 6 H+ | i.e. 4,4,14-trimethyl-cholesta-9(11),24-dien-3beta-ol | Aspergillus fumigatus CEA17 | 9(11)-dehydroergosterol + 6 ferrocytochrome b5 + 4 H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.18.10 | C4-sterol methyl oxidase | - |
Aspergillus fumigatus |
1.14.18.10 | Erg25A | isoform | Aspergillus fumigatus |
1.14.18.10 | Erg25B | isoform | Aspergillus fumigatus |
1.14.18.10 | SMO | - |
Aspergillus fumigatus |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.18.10 | malfunction | a erg25A deletion strain displays moderate susceptibility to hypoxia and the endoplasmic reticulum stress-inducing agent dithiothreitol, but is not required for virulence in murine or insect models of invasive aspergillosis | Aspergillus fumigatus |
1.14.18.10 | physiological function | isoform Erg25A is not required for virulence of Aspergillus fumigatus | Aspergillus fumigatus |