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Literature summary extracted from
- Cleavage of DNA containing 5-fluorocytosine or 5-fluorouracil by type II restriction endonucleases (2015), Bioorg. Med. Chem., 23, 6885-6890 .
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.21.4 | DNA containing F5dC + H2O | Bacillus subtilis | perfectly hydrolyzes the DNA containing 5-fluoro-dC | ? | - |
? |  |
| 3.1.21.4 | DNA containing F5dU + H2O | Bacillus subtilis | perfectly hydrolyzes the DNA containing 5-fluoro-dU | ? | - |
? | |
| 3.1.21.4 | additional information | Bacillus subtilis | no hydrolysis of DNA containing 5-methyl-dC | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.21.4 | Acetobacter pasteurianus | O52703 | - |
- |
| 3.1.21.4 | Acidithiobacillus ferrooxidans | Q4GZN8 | - |
- |
| 3.1.21.4 | Bacillus amyloliquefaciens | P23940 | - |
- |
| 3.1.21.4 | Bacillus subtilis | Q45488 | - |
- |
| 3.1.21.4 | Dolichospermum flos-aquae | E3VX87 | - |
- |
| 3.1.21.4 | Dolichospermum flos-aquae CCAP 1403/13F | E3VX87 | - |
- |
| 3.1.21.4 | Escherichia coli | P00642 | - |
- |
| 3.1.21.4 | Fuscovulum blasticum | Q6SA27 | - |
- |
| 3.1.21.4 | Gordonia rubripertincta | O85489 | - |
- |
| 3.1.21.4 | Haemophilus influenzae | P43870 | - |
- |
| 3.1.21.4 | Haemophilus influenzae ATCC 51907 | P43870 | - |
- |
| 3.1.21.4 | Klebsiella pneumoniae | P25237 | - |
- |
| 3.1.21.4 | Proteus hauseri | P23657 | - |
- |
| 3.1.21.4 | Providencia stuartii | P00640 | - |
- |
| 3.1.21.4 | Pyrococcus sp. GI-H | O93646 | - |
- |
| 3.1.21.4 | Streptomyces caespitosus | O52691 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Proteus hauseri | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Gordonia rubripertincta | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Pyrococcus sp. GI-H | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Providencia stuartii | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Fuscovulum blasticum | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Streptomyces caespitosus | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Acidithiobacillus ferrooxidans | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Klebsiella pneumoniae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Dolichospermum flos-aquae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Acetobacter pasteurianus | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Bacillus amyloliquefaciens | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Escherichia coli | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Haemophilus influenzae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Dolichospermum flos-aquae CCAP 1403/13F | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Haemophilus influenzae ATCC 51907 | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dU | Proteus hauseri | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dU | Gordonia rubripertincta | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dU | Pyrococcus sp. GI-H | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dU | Fuscovulum blasticum | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | hydrolyzes the DNA containing 5-fluoro-dU | Streptomyces caespitosus | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | hydrolyzes the DNA containing F5dU | Dolichospermum flos-aquae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | hydrolyzes the DNA containing F5dU | Escherichia coli | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Acidithiobacillus ferrooxidans | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Klebsiella pneumoniae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Acetobacter pasteurianus | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Bacillus amyloliquefaciens | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Haemophilus influenzae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | hydrolyzes the DNA containing F5dU | Dolichospermum flos-aquae CCAP 1403/13F | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-fluoro-dU + H2O | perfectly hydrolyzes the DNA containing F5dU | Haemophilus influenzae ATCC 51907 | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Fuscovulum blasticum | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | hydrolyzes the DNA containing F5dC | Escherichia coli | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | hydrolyzes the DNA containing F5dC | Haemophilus influenzae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | perfectly hydrolyzes the DNA containing 5-methyl-dC | Proteus hauseri | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | perfectly hydrolyzes the DNA containing 5-methyl-dC | Streptomyces caespitosus | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | perfectly hydrolyzes the DNA containing F5dC | Klebsiella pneumoniae | ? | - |
? | |
| 3.1.21.4 | DNA containing 5-methyl-dC + H2O | hydrolyzes the DNA containing F5dC | Haemophilus influenzae ATCC 51907 | ? | - |
? | |
| 3.1.21.4 | DNA containing F5dC + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dC | Bacillus subtilis | ? | - |
? | |
| 3.1.21.4 | DNA containing F5dU + H2O | perfectly hydrolyzes the DNA containing 5-fluoro-dU | Bacillus subtilis | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Acidithiobacillus ferrooxidans | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Dolichospermum flos-aquae | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Acetobacter pasteurianus | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Bacillus amyloliquefaciens | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Bacillus subtilis | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Gordonia rubripertincta | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis DNA containing 5-methy-dC | Pyrococcus sp. GI-H | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis DNA containing 5-methyl-dC or 5-fluoro-dU | Providencia stuartii | ? | - |
? | |
| 3.1.21.4 | additional information | no hydrolysis of DNA containing 5-methyl-dC | Dolichospermum flos-aquae CCAP 1403/13F | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.21.4 | AfeI | - |
Acidithiobacillus ferrooxidans |
| 3.1.21.4 | AflII | - |
Dolichospermum flos-aquae |
| 3.1.21.4 | aflIIR | - |
Dolichospermum flos-aquae |
| 3.1.21.4 | ApaLI | - |
Acetobacter pasteurianus |
| 3.1.21.4 | apaLIR | - |
Acetobacter pasteurianus |
| 3.1.21.4 | BamHI | - |
Bacillus amyloliquefaciens |
| 3.1.21.4 | bamHIR | - |
Bacillus amyloliquefaciens |
| 3.1.21.4 | BglII | - |
Bacillus subtilis |
| 3.1.21.4 | bglIIR | - |
Bacillus subtilis |
| 3.1.21.4 | EcoRI | - |
Escherichia coli |
| 3.1.21.4 | ecoRIR | - |
Escherichia coli |
| 3.1.21.4 | HindIII | - |
Haemophilus influenzae |
| 3.1.21.4 | hindIIIR | - |
Haemophilus influenzae |
| 3.1.21.4 | KpnI | - |
Klebsiella pneumoniae |
| 3.1.21.4 | KpnIR | - |
Klebsiella pneumoniae |
| 3.1.21.4 | NcoI | - |
Gordonia rubripertincta |
| 3.1.21.4 | ncoIR | - |
Gordonia rubripertincta |
| 3.1.21.4 | PspGI | - |
Pyrococcus sp. GI-H |
| 3.1.21.4 | PstI | - |
Providencia stuartii |
| 3.1.21.4 | pstIR | - |
Providencia stuartii |
| 3.1.21.4 | PvuII | - |
Proteus hauseri |
| 3.1.21.4 | RsaI | - |
Fuscovulum blasticum |
| 3.1.21.4 | ScaI | - |
Streptomyces caespitosus |
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