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Literature summary extracted from

  • Abd-El-Haliem, A.M.; Vossen, J.H.; van Zeijl, A.; Dezhsetan, S.; Testerink, C.; Seidl, M.F.; Beck, M.; Strutt, J.; Robatzek, S.; Joosten, M.H.A.J.
    Biochemical characterization of the tomato phosphatidylinositol-specific phospholipase C (PI-PLC) family and its role in plant immunity (2016), Biochim. Biophys. Acta, 1861, 1365-1378 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.4.11 expressed in Escherichia coli and Nicotiana benthamiana Solanum lycopersicum

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.11 additional information not inhibited by U-73343 Solanum lycopersicum
3.1.4.11 U-73122
-
 Solanum lycopersicum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.4.11 Ca2+ required Solanum lycopersicum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O Solanum lycopersicum
-
 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.11 Solanum lycopersicum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.11 1-phosphatidyl-1D-myo-inositol + H2O
-
 Solanum lycopersicum 1D-myo-inositol 1-phosphate + diacylglycerol
-
 ?
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O
-
 Solanum lycopersicum 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O preferred substrate Solanum lycopersicum 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol
-
 ?
3.1.4.11 1-phosphatidyl-1D-myo-inositol 4-phosphate + H2O
-
 Solanum lycopersicum 1D-myo-inositol 1,4-bisphosphate + diacylglycerol
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.4.11 ? x * 91000, isoform PLC2, calculated from amino acid sequence Solanum lycopersicum
3.1.4.11 ? x * 92000, isoform PLC6, calculated from amino acid sequence Solanum lycopersicum
3.1.4.11 ? x * 93600, isoform PLC4, calculated from amino acid sequence Solanum lycopersicum
3.1.4.11 ? x * 94300, isoform PLC3, calculated from amino acid sequence Solanum lycopersicum
3.1.4.11 ? x * 95000, isoform PLC5, calculated from amino acid sequence Solanum lycopersicum
3.1.4.11 ? x * 95500, isoform PLC1, calculated from amino acid sequence Solanum lycopersicum

Synonyms

EC Number Synonyms Comment Organism
3.1.4.11 phosphatidylinositol-specific phospholipase C
-
 Solanum lycopersicum
3.1.4.11 PLC1 isoform Solanum lycopersicum
3.1.4.11 PLC2 isoform Solanum lycopersicum
3.1.4.11 PLC3 isoform Solanum lycopersicum
3.1.4.11 PLC4 isoform Solanum lycopersicum
3.1.4.11 PLC5 isoform Solanum lycopersicum
3.1.4.11 PLC6 isoform Solanum lycopersicum

General Information

EC Number General Information Comment Organism
3.1.4.11 physiological function the enzyme is required for both specific effector- and more general pattern-triggered immunity Solanum lycopersicum