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Literature summary extracted from

  • Foster, J.; Luo, B.; Nakata, P.A.
    An oxalyl-CoA dependent pathway of oxalate catabolism plays a role in regulating calcium oxalate crystal accumulation and defending against oxalate-secreting phytopathogens in Medicago truncatula (2016), PLoS ONE, 11, e0149850 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.2.1.8 expressed in Escherichia coli BLR(DE3) cells and Nicotiana tabacum leaves Medicago truncatula

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.8 0.081
-
 oxalate at pH 8.0, temperature not specified in the publication Medicago truncatula

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.8 cytosol
-
 Medicago truncatula 5829
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.2.1.8 ATP + oxalate + CoA Medicago truncatula
-
 AMP + diphosphate + oxalyl-CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.8 Medicago truncatula
-
 ecotype R108
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.2.1.8 Ni-NTA column chromatography and Sephadex G-25 gel filtration Medicago truncatula

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.8 leaf
-
 Medicago truncatula
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.8 ATP + oxalate + CoA
-
 Medicago truncatula AMP + diphosphate + oxalyl-CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
6.2.1.8 ? x * 50000, SDS-PAGE Medicago truncatula

Synonyms

EC Number Synonyms Comment Organism
6.2.1.8 AAE3
-
 Medicago truncatula
6.2.1.8 Oxalyl-CoA synthetase
-
 Medicago truncatula

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.8 8
-
-
 Medicago truncatula

Cofactor

EC Number Cofactor Comment Organism Structure
6.2.1.8 ATP
-
 Medicago truncatula

General Information

EC Number General Information Comment Organism
6.2.1.8 malfunction reduction of enzyme expression increases susceptibility of Medicago truncatula to the oxalate-secreting fungal pathogen Sclerotinia sclerotiorum and results in the accumulation of druse crystals of calcium oxalate Medicago truncatula