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Literature summary extracted from

  • Fitzpatrick, A.H.; Bhandari, J.; Crowell, D.N.
    Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis (2011), Plant J., 66, 1078-1088.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.216 expression Saccharomyces cerevisiae Arabidopsis thaliana
2.7.4.32 expression Saccharomyces cerevisiae Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.216 chloroplast
-
 Arabidopsis thaliana 9507
-
2.7.1.216 membrane
-
 Arabidopsis thaliana 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.216 Arabidopsis thaliana Q67ZM7
-
-
2.7.4.32 Arabidopsis thaliana
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.216 ATP + (2E,6E)-farnesol
-
 Arabidopsis thaliana ADP + (2E,6E)-farnesyl phosphate
-
 ?
2.7.1.216 ATP + (2E,6E)-geranylgeraniol
-
 Arabidopsis thaliana ADP + (2E,6E)-geranylgeranyl phosphate
-
 ?
2.7.1.216 ATP + geraniol
-
 Arabidopsis thaliana ADP + geranyl phosphate
-
 ?
2.7.1.216 CTP + (2E,6E)-farnesol
-
 Arabidopsis thaliana CDP + (2E,6E)-farnesyl phosphate
-
 ?
2.7.1.216 GTP + (2E,6E)-farnesol
-
 Arabidopsis thaliana GDP + (2E,6E)-farnesyl phosphate
-
 ?
2.7.1.216 additional information phosphate donor substrates in decreasing activity: CTP, ATP, GTP and UDP. Geraniol and geranylgeraniol are phosphorylated to a lesser extent than farnesol. The enzyme does not show farnesol phosphate kinase activity Arabidopsis thaliana ?
-
 ?
2.7.1.216 UTP + (2E,6E)-farnesol
-
 Arabidopsis thaliana UDP + (2E,6E)-farnesyl phosphate
-
 ?
2.7.4.32 CTP + (2E,6E)-farnesyl phosphate
-
 Arabidopsis thaliana CDP + (2E,6E)-farnesyl diphosphate
-
 ?
2.7.4.32 additional information the enzyme is specific for CTP as phosphate donor Arabidopsis thaliana ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.216 At5g58560
-
 Arabidopsis thaliana
2.7.1.216 FOLK
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
2.7.1.216 Arabidopsis thaliana in wild-type plants, exogenous abscisic acid represses FOLK gene expression down
2.7.4.32 Arabidopsis thaliana in wild-type plants, exogenous abscisic acid represses FOLK gene expression down

General Information

EC Number General Information Comment Organism
2.7.1.216 physiological function loss-of-function mutations in the FOLK gene abolish farnesol kinase activity, cause an abscisic acid-hypersensitive phenotype and promote the development of supernumerary carpels under water-stress conditions Arabidopsis thaliana