Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Gupta, A.; Toscano, S.; Trivedi, D.; Jones, D.R.; Mathre, S.; Clarke, J.H.; Divecha, N.; Raghu, P.
    Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development (2013), Proc. Natl. Acad. Sci. USA, 110, 5963-5968.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.7.1.149 D271K inactive Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate Drosophila melanogaster
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.149 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.149 larva
-
 Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.149 ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate
-
 Drosophila melanogaster ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.149 phosphatidylinositol 5-phosphate 4-kinase
-
 Drosophila melanogaster
2.7.1.149 PIP4K
-
 Drosophila melanogaster
2.7.1.149 PIP4KIIalpha
-
 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.7.1.149 malfunction loss-of-function mutants in PIP4K show reduced body weight and prolonged larval development Drosophila melanogaster
2.7.1.149 physiological function the enzyme regulates TOR signaling and cell growth during Drosophila development Drosophila melanogaster