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Literature summary extracted from

  • Nascimento, F.; Rossi, M.; Soares, C.; McConkey, B.; Glick, B.
    New insights into 1-aminocyclopropane-1-carboxylate (ACC) deaminase phylogeny, evolution and ecological significance (2014), PLoS ONE, 9, e99168.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
3.5.99.7 E295S/L322T the mutations lead to a loss of enzyme activity against 1-aminocyclopropane-1-carboxylate Pseudomonas putida

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.5.99.7 0.25
-
 D-Cystine pH and temperature not specified in the publication Arabidopsis thaliana
3.5.99.7 0.34
-
 D-Cystine mutant enzyme E295S/L322T, pH and temperature not specified in the publication Pseudomonas putida
3.5.99.7 0.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Methylobacterium nodulans
3.5.99.7 1.1
-
 beta,beta-difluoro-D-alanine pH and temperature not specified in the publication Pseudomonas sp.
3.5.99.7 1.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Methylobacterium radiotolerans
3.5.99.7 2.6
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Cyberlindnera saturnus
3.5.99.7 3.4
-
 1-aminocyclopropane-1-carboxylate wild type enzyme, pH and temperature not specified in the publication Pseudomonas putida
3.5.99.7 4.4
-
 1-amino-2-vinylcyclopropane-1-carboxylic acid pH and temperature not specified in the publication Pseudomonas sp.
3.5.99.7 4.8
-
 1-aminocyclopropane-1-carboxylate pH and temperature not specified in the publication Penicillium citrinum
3.5.99.7 5.4
-
 beta-Chloro-D-alanine pH and temperature not specified in the publication Pseudomonas sp.
3.5.99.7 36.2
-
 DL-coronamic acid pH and temperature not specified in the publication Pseudomonas sp.
3.5.99.7 56
-
 O-acetyl-D-serine pH and temperature not specified in the publication Pseudomonas sp.
3.5.99.7 97
-
 D-vinylglycine pH and temperature not specified in the publication Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Arabidopsis thaliana
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Pseudomonas sp.
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Penicillium citrinum
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Cyberlindnera saturnus
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Methylobacterium radiotolerans
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Pseudomonas putida
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Bradyrhizobium japonicum
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Methylobacterium nodulans
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Bradyrhizobium japonicum USDA 110
-
 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O Pseudomonas putida UW4
-
 2-oxobutanoate + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.99.7 Arabidopsis thaliana
-
-
-
3.5.99.7 Bradyrhizobium japonicum Q89XR6
-
-
3.5.99.7 Bradyrhizobium japonicum USDA 110 Q89XR6
-
-
3.5.99.7 Cyberlindnera saturnus
-
-
-
3.5.99.7 Methylobacterium nodulans
-
-
-
3.5.99.7 Methylobacterium radiotolerans
-
-
-
3.5.99.7 Penicillium citrinum
-
-
-
3.5.99.7 Pseudomonas putida Q5PWZ8
-
-
3.5.99.7 Pseudomonas putida UW4 Q5PWZ8
-
-
3.5.99.7 Pseudomonas sp.
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.99.7 1-amino-2-vinylcyclopropane-1-carboxylic acid + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Arabidopsis thaliana 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas sp. 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Penicillium citrinum 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Cyberlindnera saturnus 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Methylobacterium radiotolerans 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas putida 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Bradyrhizobium japonicum 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Methylobacterium nodulans 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Bradyrhizobium japonicum USDA 110 2-oxobutanoate + NH3
-
 ?
3.5.99.7 1-aminocyclopropane-1-carboxylate + H2O
-
 Pseudomonas putida UW4 2-oxobutanoate + NH3
-
 ?
3.5.99.7 beta,beta-dichloro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 beta,beta-difluoro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 beta-chloro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 beta-fluoro-D-alanine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Arabidopsis thaliana ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Cyberlindnera saturnus ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Methylobacterium radiotolerans ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Pseudomonas putida ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Methylobacterium nodulans ?
-
 ?
3.5.99.7 D-cystine + H2O
-
 Pseudomonas putida UW4 ?
-
 ?
3.5.99.7 D-erythro-2-amino-3-chlorobutyrate + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 D-serine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 D-serine + H2O
-
 Penicillium citrinum ?
-
 ?
3.5.99.7 D-serine + H2O
-
 Cyberlindnera saturnus ?
-
 ?
3.5.99.7 D-serine + H2O
-
 Bradyrhizobium japonicum ?
-
 ?
3.5.99.7 D-serine + H2O
-
 Bradyrhizobium japonicum USDA 110 ?
-
 ?
3.5.99.7 D-threo-2-amino-3-fluorobutyrate + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 D-vinylglycine + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 DL-coronamic acid + H2O
-
 Pseudomonas sp. ?
-
 ?
3.5.99.7 DL-coronamic acid + H2O
-
 Penicillium citrinum ?
-
 ?
3.5.99.7 DL-coronamic acid + H2O
-
 Cyberlindnera saturnus ?
-
 ?
3.5.99.7 L-cystine + H2O
-
 Methylobacterium radiotolerans ?
-
 ?
3.5.99.7 L-cystine + H2O
-
 Methylobacterium nodulans ?
-
 ?
3.5.99.7 L-serine + H2O
-
 Penicillium citrinum ?
-
 ?
3.5.99.7 additional information 1-aminocyclopentane-1-carboxylate, L-homoserine, L-Thr, L-Tryp, L-Met, L-Tyr, L-Cys, and L-aminobutyrate are not a functional substrate Pseudomonas sp. ?
-
 ?
3.5.99.7 additional information beta-chloro-D-alanine and O-acetyl-D-serine are not a functional substrate Cyberlindnera saturnus ?
-
 ?
3.5.99.7 additional information beta-chloro-D-alanine is not a functional substrate Bradyrhizobium japonicum ?
-
 ?
3.5.99.7 additional information DL-allocoronamic acid and dimethyl-1-aminocyclopropane-1-carboxylic acid are not a functional substrate Penicillium citrinum ?
-
 ?
3.5.99.7 additional information beta-chloro-D-alanine is not a functional substrate Bradyrhizobium japonicum USDA 110 ?
-
 ?
3.5.99.7 O-acetyl-D-serine + H2O
-
 Pseudomonas sp. ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.99.7 ACC deaminase
-
 Arabidopsis thaliana
3.5.99.7 ACC deaminase
-
 Pseudomonas sp.
3.5.99.7 ACC deaminase
-
 Penicillium citrinum
3.5.99.7 ACC deaminase
-
 Cyberlindnera saturnus
3.5.99.7 ACC deaminase
-
 Methylobacterium radiotolerans
3.5.99.7 ACC deaminase
-
 Pseudomonas putida
3.5.99.7 ACC deaminase
-
 Bradyrhizobium japonicum
3.5.99.7 ACC deaminase
-
 Methylobacterium nodulans
3.5.99.7 AcdS
-
 Arabidopsis thaliana
3.5.99.7 AcdS
-
 Pseudomonas sp.
3.5.99.7 AcdS
-
 Penicillium citrinum
3.5.99.7 AcdS
-
 Cyberlindnera saturnus
3.5.99.7 AcdS
-
 Methylobacterium radiotolerans
3.5.99.7 AcdS
-
 Pseudomonas putida
3.5.99.7 AcdS
-
 Bradyrhizobium japonicum
3.5.99.7 AcdS
-
 Methylobacterium nodulans