Literature summary extracted from

Drozdikova, E.; Garaiova, M.; Csaky, Z.; Obernauerova, M.; Hapala, I.
Production of squalene by lactose-fermenting yeast Kluyveromyces lactis with reduced squalene epoxidase activity (2015), Lett. Appl. Microbiol., 61, 77-84.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.14.17	terbinafine	specific inhibitor	Kluyveromyces lactis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.14.17	squalene + [reduced NADPH-hemoprotein reductase] + O2	Kluyveromyces lactis	-	(3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.14.17	Kluyveromyces lactis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.14.17	squalene + [reduced NADPH-hemoprotein reductase] + O2	-	Kluyveromyces lactis	(3S)-2,3-epoxy-2,3-dihydrosqualene + [oxidized NADPH-hemoprotein reductase] + H2O	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.14.14.17	squalene epoxidase	-	Kluyveromyces lactis

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Release 2023.1 (January 2023)