Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Bao, Y.; Zhang, X.; Jiang, Q.; Xue, T.; Sun, B.
    Pfs promotes autolysis-dependent release of eDNA and biofilm formation in Staphylococcus aureus (2015), Med. Microbiol. Immunol., 204, 215-226.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.2.16 S-methyl-5'-thioadenosine + H2O Staphylococcus aureus
-
 S-methyl-5-thio-D-ribose + adenine
-
 ?
3.2.2.16 S-methyl-5'-thioadenosine + H2O Staphylococcus aureus NCTC 8325
-
 S-methyl-5-thio-D-ribose + adenine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.16 Staphylococcus aureus
-
-
-
3.2.2.16 Staphylococcus aureus NCTC 8325
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.16 S-methyl-5'-thioadenosine + H2O
-
 Staphylococcus aureus S-methyl-5-thio-D-ribose + adenine
-
 ?
3.2.2.16 S-methyl-5'-thioadenosine + H2O
-
 Staphylococcus aureus NCTC 8325 S-methyl-5-thio-D-ribose + adenine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.2.16 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
-
 Staphylococcus aureus
3.2.2.16 Pfs
-
 Staphylococcus aureus

General Information

EC Number General Information Comment Organism
3.2.2.16 malfunction the deletion of the enzyme gene reduces bacterial clumping ability and results in the decreased biofilm formation. The gene mutation also significantly decreases the amount of eDNA present in the biofilm and the cell autolysis Staphylococcus aureus
3.2.2.16 physiological function the enzyme promotes autolysis-dependent release of eDNA and biofilm formation Staphylococcus aureus