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Literature summary extracted from

  • Gräwert, T.; Hohmann, H.P.; Kindermann, M.; Duval, S.; Bacher, A.; Fischer, M.
    Inhibition of methyl-CoM reductase from Methanobrevibacter ruminantium by 2-bromoethanesulfonate (2014), J. Agric. Food Chem., 62, 12487-12490.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.8.4.1 2-bromoethanesulfonate
-
 Methanobrevibacter ruminantium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.8.4.1 28700
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium
2.8.4.1 47100
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium
2.8.4.1 59800
-
 x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium

Organism

EC Number Organism UniProt Comment Textmining
2.8.4.1 Methanobrevibacter ruminantium
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.8.4.1 0.006
-
 pH and temperature not specified in the publication Methanobrevibacter ruminantium

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.4.1 methyl-CoM + CoB
-
 Methanobrevibacter ruminantium CoM-S-S-CoB + methane
-
 ?

Subunits

EC Number Subunits Comment Organism
2.8.4.1 ? x * 59800 + x * 47100 + x * 28700, SDS-PAGE Methanobrevibacter ruminantium

Synonyms

EC Number Synonyms Comment Organism
2.8.4.1 methyl-CoM reductase
-
 Methanobrevibacter ruminantium

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.8.4.1 0.0004
-
 pH and temperature not specified in the publication Methanobrevibacter ruminantium 2-bromoethanesulfonate

General Information

EC Number General Information Comment Organism
2.8.4.1 metabolism the enzyme catalyzes the final step of methanogenesis in Methanobrevibacter ruminantium Methanobrevibacter ruminantium