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Literature summary extracted from

  • Min, Y.; Lv, H.; Zheng, Y.
    Fusion PCR-targeted tylCV gene deletion of Streptomyces fradiae for producing desmycosin, the direct precursor of tilmicosin (2007), Process Biochem., 42, 729-733.
No PubMed abstract available

Application

EC Number Application Comment Organism
2.4.1.318 synthesis the disruption of the tylCV gene results in the accumulation of desmycosin, the direct precursor of tilmicosin. After optimization of the culture conditions, the yield of desmycosin reaches 7.3 g/l in a 5 l jar fermentor Streptomyces fradiae

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.318 Streptomyces fradiae Q9XC67
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Synonyms

EC Number Synonyms Comment Organism
2.4.1.318 mycarosyltransferase
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Streptomyces fradiae
2.4.1.318 tylCV
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Streptomyces fradiae

General Information

EC Number General Information Comment Organism
2.4.1.318 physiological function the disruption of the tylCV gene results in the accumulation of desmycosin, the direct precursor of tilmicosin Streptomyces fradiae