EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.15.31 | heterologous expression of the gene together with ncsB and ncsB1 in Streptomyces lividans TK24 | Streptomyces carzinostaticus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | Streptomyces carzinostaticus | the enzyme is involved in the biosynthesis of the enediyne antibiotic neocarzinostatin | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | Streptomyces carzinostaticus ATCC 15944 | the enzyme is involved in the biosynthesis of the enediyne antibiotic neocarzinostatin | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.15.31 | Streptomyces carzinostaticus | Q84HB6 | - |
- |
1.14.15.31 | Streptomyces carzinostaticus ATCC 15944 | Q84HB6 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | - |
Streptomyces carzinostaticus | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | the enzyme is involved in the biosynthesis of the enediyne antibiotic neocarzinostatin | Streptomyces carzinostaticus | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | - |
Streptomyces carzinostaticus ATCC 15944 | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
1.14.15.31 | 2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 | the enzyme is involved in the biosynthesis of the enediyne antibiotic neocarzinostatin | Streptomyces carzinostaticus ATCC 15944 | 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.15.31 | NcsB3 | - |
Streptomyces carzinostaticus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.15.31 | cytochrome P-450 | a heme-thiolate protein | Streptomyces carzinostaticus |