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Literature summary extracted from

  • Tocchini-Valentini, G.D.; Fruscoloni, P.; Tocchini-Valentini, G.P.
    Processing of multiple-intron-containing pretRNA (2009), Proc. Natl. Acad. Sci. USA, 106, 20246-20251.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.16 pre-tRNA Saccharolobus solfataricus processing of multiple-intron-containing pretRNA. In these multiple-intron-containing pretRNAs, the introns are nested one inside the other and the pretRNA folds into a conformation that presumably allows the splicing of the last intron only after the splicing of the others. The tRNA splicing endonuclease and the ligase, through a series of cleavages and ligations, should lead to the formation of mature tRNA ?
-
 ?
4.6.1.16 pre-tRNA Methanocaldococcus jannaschii processing of multiple-intron-containing pretRNA. In these multiple-intron-containing pretRNAs, the introns are nested one inside the other and the pretRNA folds into a conformation that presumably allows the splicing of the last intron only after the splicing of the others. The tRNA splicing endonuclease and the ligase, through a series of cleavages and ligations, should lead to the formation of mature tRNA ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.16 Methanocaldococcus jannaschii
-
-
-
4.6.1.16 Saccharolobus solfataricus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.16 pre-tRNA
-
 Saccharolobus solfataricus ?
-
 ?
4.6.1.16 pre-tRNA
-
 Methanocaldococcus jannaschii ?
-
 ?
4.6.1.16 pre-tRNA processing of multiple-intron-containing pretRNA. In these multiple-intron-containing pretRNAs, the introns are nested one inside the other and the pretRNA folds into a conformation that presumably allows the splicing of the last intron only after the splicing of the others. The tRNA splicing endonuclease and the ligase, through a series of cleavages and ligations, should lead to the formation of mature tRNA Saccharolobus solfataricus ?
-
 ?
4.6.1.16 pre-tRNA processing of multiple-intron-containing pretRNA. In these multiple-intron-containing pretRNAs, the introns are nested one inside the other and the pretRNA folds into a conformation that presumably allows the splicing of the last intron only after the splicing of the others. The tRNA splicing endonuclease and the ligase, through a series of cleavages and ligations, should lead to the formation of mature tRNA Methanocaldococcus jannaschii ?
-
 ?

Subunits

EC Number Subunits Comment Organism
4.6.1.16 heterotetramer
-
 Saccharolobus solfataricus
4.6.1.16 homotetramer
-
 Methanocaldococcus jannaschii