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Literature summary extracted from

  • Harvey, A.R.; Ward, M.; Archer, D.B.
    Identification and characterisation of eroA and ervA, encoding two putative thiol oxidases from Aspergillus niger (2010), Gene, 461, 32-41.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.3.2 endoplasmic reticulum isoform EroA is retained in the ER lumen by a C-terminal retention motif Aspergillus niger 5783
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Organism

EC Number Organism UniProt Comment Textmining
1.8.3.2 Aspergillus niger
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1.8.3.2 Aspergillus niger N402
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Expression

EC Number Organism Comment Expression
1.8.3.2 Aspergillus niger isoform ErvA is slightly downregulated in response to dithiothreitol stress yet up-regulated in response to expression of a heterologous protein additional information
1.8.3.2 Aspergillus niger isoform EroA is transcriptionally up-regulated in response to endoplasmic reticulum stress up

General Information

EC Number General Information Comment Organism
1.8.3.2 physiological function enzyme gene eroA gene is essential for viability. It is able to complement the ERO1 function in the Saccharomyces cerevisiae ero1-1 mutant Aspergillus niger
1.8.3.2 physiological function isoform ErvA gene ervA does not have an obvious role in the secretion of native proteins, including glucoamylase. It is able to complement the ERO1 function in the Saccharomyces cerevisiae ero1-1 mutant Aspergillus niger