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Literature summary extracted from

  • Avilan, L.; Maberly, S.; Mekhalfi, M.; Plateau, J.; Puppo, C.; Gontero, B.
    Regulation of glyceraldehyde-3-phosphate dehydrogenase in the eustigmatophyte Pseudocharaciopsis ovalis is intermediate between a chlorophyte and a diatom (2012), Eur. J. Phycol., 47, 207-215.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.9 NADP+ there is a 1.5fold increase of enzyme activity with NADP+ at concentrations higher than 0.5 mM Asterionella formosa
1.2.1.9 NADP+ there is a small increase of enzyme activity with NADP+ at concentrations higher than 0.5 mM Chlamydomonas reinhardtii
1.2.1.9 NADP+ there is a small increase of enzyme activity with NADP+ at concentrations higher than 0.5 mM Pseudocharaciopsis ovalis

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.9 NADPH NADPH causes a large inhibition in enzyme activity even at very low concentrations (0.01-0.02?mM) Asterionella formosa
1.2.1.9 NADPH under oxidized conditions, NADPH causes a large inhibition in enzyme activity even at very low concentrations (0.01-0.02 mM) Pseudocharaciopsis ovalis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O Chlamydomonas reinhardtii
-
 3-phospho-D-glycerate + NADPH + H+
-
 ?
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O Pseudocharaciopsis ovalis
-
 3-phospho-D-glycerate + NADPH + H+
-
 ?
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O Asterionella formosa
-
 3-phospho-D-glycerate + NADPH + H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.9 Asterionella formosa
-
-
-
1.2.1.9 Chlamydomonas reinhardtii
-
-
-
1.2.1.9 Pseudocharaciopsis ovalis
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O
-
 Chlamydomonas reinhardtii 3-phospho-D-glycerate + NADPH + H+
-
 ?
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O
-
 Pseudocharaciopsis ovalis 3-phospho-D-glycerate + NADPH + H+
-
 ?
1.2.1.9 D-glyceraldehyde 3-phosphate + NADP+ + H2O
-
 Asterionella formosa 3-phospho-D-glycerate + NADPH + H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.9 NADPH-dependent GAPDH
-
 Chlamydomonas reinhardtii
1.2.1.9 NADPH-dependent GAPDH
-
 Pseudocharaciopsis ovalis
1.2.1.9 NADPH-dependent GAPDH
-
 Asterionella formosa

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.2.1.9 6.2 8.1
-
 Asterionella formosa
1.2.1.9 8 9
-
 Chlamydomonas reinhardtii
1.2.1.9 8 9
-
 Pseudocharaciopsis ovalis

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.9 NADP+
-
 Chlamydomonas reinhardtii
1.2.1.9 NADP+
-
 Pseudocharaciopsis ovalis
1.2.1.9 NADP+
-
 Asterionella formosa

Expression

EC Number Organism Comment Expression
1.2.1.9 Chlamydomonas reinhardtii the enzyme is down-regulated in the dark down
1.2.1.9 Pseudocharaciopsis ovalis the enzyme is down-regulated in the dark down
1.2.1.9 Asterionella formosa the enzyme is not down-regulated in the dark additional information