EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.8.4.1 | 0.03 | - |
CH3-S-CoM | with SH-CoB6 as cosubstrate, pH not specified in the publication, at 25°C | Methanothermobacter marburgensis | |
2.8.4.1 | 0.08 | - |
SH-CoB6 | pH not specified in the publication, at 25°C | Methanothermobacter marburgensis | |
2.8.4.1 | 0.28 | - |
CH3-S-CoM | with SH-CoB5 as cosubstrate, pH not specified in the publication, at 25°C | Methanothermobacter marburgensis | |
2.8.4.1 | 0.34 | - |
SH-CoB5 | pH not specified in the publication, at 25°C | Methanothermobacter marburgensis |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.8.4.1 | Nickel | the active site of the enzyme contains an essential redox-active nickel tetrapyrrole cofactor, coenzyme F430, which is active in the Ni(I) state | Methanothermobacter marburgensis |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.4.1 | CH3-S-CoM + SH-CoB | Methanothermobacter marburgensis | - |
CoM-S-S-CoB + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB | Methanothermobacter marburgensis OCM82 | - |
CoM-S-S-CoB + methane | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.4.1 | Methanothermobacter marburgensis | - |
- |
- |
2.8.4.1 | Methanothermobacter marburgensis OCM82 | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.4.1 | CH3-S-CoM + SH-CoB | - |
Methanothermobacter marburgensis | CoM-S-S-CoB + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB | - |
Methanothermobacter marburgensis OCM82 | CoM-S-S-CoB + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB5 | - |
Methanothermobacter marburgensis | CoM-S-S-CoB5 + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB5 | - |
Methanothermobacter marburgensis OCM82 | CoM-S-S-CoB5 + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB6 | methanogenesis occurs 1000fold more slowly than with SH-CoB | Methanothermobacter marburgensis | CoM-S-S-CoB6 + methane | - |
? | |
2.8.4.1 | CH3-S-CoM + SH-CoB6 | methanogenesis occurs 1000fold more slowly than with SH-CoB | Methanothermobacter marburgensis OCM82 | CoM-S-S-CoB6 + methane | - |
? | |
2.8.4.1 | additional information | no activity with SH-CoB8 or SH-CoB9 | Methanothermobacter marburgensis | ? | - |
? | |
2.8.4.1 | additional information | no activity with SH-CoB8 or SH-CoB9 | Methanothermobacter marburgensis OCM82 | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.4.1 | MCR | - |
Methanothermobacter marburgensis |
2.8.4.1 | methyl-coenzyme M reductase | - |
Methanothermobacter marburgensis |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.8.4.1 | F-430 | the active site of the enzyme contains an essential redox-active nickel tetrapyrrole cofactor, coenzyme F430, which is active in the Ni(I) state | Methanothermobacter marburgensis |