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Literature summary extracted from

  • Yoon, H.J.; Kang, J.Y.; Mikami, B.; Lee, H.H.; Suh, S.W.
    Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine (2011), Mol. Cells, 32, 431-435.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.7.3
-
 Enterococcus faecalis

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.7.3 ligand-unbound state and in complex with ATP and pantetheine, using 3.5 M sodium formate and 100 mM Tris-HCl (pH 8.5) Enterococcus faecalis

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.3 pantetheine potent inhibitor Enterococcus faecalis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.3 Mg2+ the enzyme contains a catalytic Mg2+ ion Enterococcus faecalis

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.3 Enterococcus faecalis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.7.3
-
 Enterococcus faecalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.3 ATP + pantetheine 4'-phosphate
-
 Enterococcus faecalis diphosphate + 3'-dephospho-CoA
-
 r

Subunits

EC Number Subunits Comment Organism
2.7.7.3 homohexamer x-ray crystallography Enterococcus faecalis

Synonyms

EC Number Synonyms Comment Organism
2.7.7.3 phosphopantetheine adenylyltransferase
-
 Enterococcus faecalis
2.7.7.3 PPAT
-
 Enterococcus faecalis