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Literature summary extracted from

  • Yang, N.; Ma, P.; Lang, J.; Zhang, Y.; Deng, J.; Ju, X.; Zhang, G.; Jiang, C.
    Phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry (2012), J. Biol. Chem., 287, 8457-8467.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.67 LY294002 treatment inhibits SARS-CoV S-mediated entry into VeroE6 cells Chlorocebus sabaeus
2.7.1.67 Wortmannin treatment inhibits SARS-CoV S-mediated entry into VeroE6 cells Chlorocebus sabaeus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.67 Chlorocebus sabaeus
-
-
-
2.7.1.67 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.67 HEK-293 cell
-
 Homo sapiens
-
2.7.1.67 Vero-E6 cell
-
 Chlorocebus sabaeus
-

Synonyms

EC Number Synonyms Comment Organism
2.7.1.67 phosphatidylinositol 4-kinase IIIbeta
-
 Homo sapiens
2.7.1.67 phosphatidylinositol 4-kinase IIIbeta
-
 Chlorocebus sabaeus

General Information

EC Number General Information Comment Organism
2.7.1.67 malfunction knockdown of isozyme phosphatidylinositol 4-kinase IIIbeta inhibits SARS-CoV S-mediated entry into VeroE6 cells Chlorocebus sabaeus
2.7.1.67 physiological function isozyme phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry, overview Chlorocebus sabaeus
2.7.1.67 physiological function isozyme phosphatidylinositol 4-kinase IIIbeta is required for severe acute respiratory syndrome coronavirus spike-mediated cell entry. PI4P plays an essential role in SARS-CoV spike-mediated entry, which is regulated by the PI4P lipid microenvironment, overview Homo sapiens