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Literature summary extracted from

  • Li, W.; Zhang, P.; Zuccolo, A.J.; Zheng, R.B.; Ling, C.C.
    CST-II’s recognition domain for acceptor substrates in alpha-(2->8)-sialylations (2011), Carbohydr. Res., 346, 1692-1704.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.3.8 Mn2+ required Campylobacter jejuni

Organism

EC Number Organism UniProt Comment Textmining
2.4.3.8 Campylobacter jejuni
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-
-
2.4.3.8 Campylobacter jejuni OH4384
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.3.8 CMP-N-acetylneuraminate + (11-azidoundecyl 5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosid)onic acid
-
 Campylobacter jejuni CMP + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid 12%, 7.7%, 5.3%, 4.5%, and 2.2% yield, respectively ?
2.4.3.8 CMP-N-acetylneuraminate + (11-azidoundecyl 5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosid)onic acid
-
 Campylobacter jejuni OH4384 CMP + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + 11-azidoundecyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid 12%, 7.7%, 5.3%, 4.5%, and 2.2% yield, respectively ?
2.4.3.8 CMP-N-acetylneuraminate + (methyl S-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosyl)onic acid
-
 Campylobacter jejuni CMP + methyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + methyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid 17% and 10.1% yield, respectively ?
2.4.3.8 CMP-N-acetylneuraminate + (methyl S-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosyl)onic acid
-
 Campylobacter jejuni OH4384 CMP + methyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid + methyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid 17% and 10.1% yield, respectively ?
2.4.3.8 CMP-N-acetylneuraminate + 4-chlorophenyl 6-S-(5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-1,6-dithio-beta-D-galactopyranoside
-
 Campylobacter jejuni CMP + 4-chlorophenyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-S-1,6-dithio-beta-D-galactopyranoside
-
 ?
2.4.3.8 CMP-N-acetylneuraminate + 4-chlorophenyl 6-S-(5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-1,6-dithio-beta-D-galactopyranoside
-
 Campylobacter jejuni OH4384 CMP + 4-chlorophenyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-S-1,6-dithio-beta-D-galactopyranoside
-
 ?
2.4.3.8 CMP-N-acetylneuraminate + beta-sialic acid
-
 Campylobacter jejuni CMP + alpha-N-acetylneuraminyl-(2->8)-beta-N-acetylneuraminate 21.5% yield ?
2.4.3.8 CMP-N-acetylneuraminate + beta-sialic acid
-
 Campylobacter jejuni OH4384 CMP + alpha-N-acetylneuraminyl-(2->8)-beta-N-acetylneuraminate 21.5% yield ?
2.4.3.8 CMP-N-acetylneuraminate + methyl S-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->6)-(6-thio-beta-D-galactopyranosyl)-(1->4)-O-beta-D-glucopyranoside
-
 Campylobacter jejuni CMP + methyl O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galactonon-2-ulopyranosylonic acid)-(2->8)-(5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosylonic acid)-(2->6)-(6-thio-beta-D-galactopyranosyl)-(1->4)-beta-D-glucopyranoside 19% yield ?
2.4.3.8 additional information (4-chlorophenyl 5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosid)onic acid is no substrate Campylobacter jejuni ?
-
 ?
2.4.3.8 additional information (4-chlorophenyl 5-acetamido-3,5-dideoxy-2-thio-D-glycero-alpha-D-galacto-non-2-ulopyranosid)onic acid is no substrate Campylobacter jejuni OH4384 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.3.8 CST-II
-
 Campylobacter jejuni