Literature summary extracted from

Sohng, J.K.; Kim, H.J.; Nam, D.H.; Lim, D.O.; Han, J.M.; Lee, H.J.; Yoo, J.C.
Cloning, expression, and biological function of a dTDP-deoxyglucose epimerase (gerF) gene from Streptomyces sp. GERI-155 (2004), Biotechnol. Lett., 26, 185-191.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
5.1.3.27	expression in Eschericha coli using recombinant expression vector pHJ3	Streptomyces sp.

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.1.3.27	Streptomyces sp.	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
5.1.3.27	recombinant enzyme	Streptomyces sp.

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5.1.3.27	dTDP-4-dehydro-6-deoxy-alpha-D-glucose	dTDP-4-dehydro-6-deoxy-D-glucopyranose. The enzyme exhibits epimerase activity, as evidenced by the detection of maltol, the decomposition product of the activated intermediate	Streptomyces sp.	dTDP-4-dehydro-6-deoxy-beta-D-gulose	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
5.1.3.27	dTDP-4-keto-6-deoxy-D-glucose 3-epimerase	-	Streptomyces sp.
5.1.3.27	dTDP-deoxyglucose 3-epimerase	-	Streptomyces sp.
5.1.3.27	GerF	-	Streptomyces sp.

General Information

EC Number	General Information	Comment	Organism
5.1.3.27	physiological function	the enzyme is involved in the mycinose biosynthetic pathway of several macrolide antibiotics	Streptomyces sp.

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Release 2023.1 (January 2023)