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Literature summary extracted from

  • Sahun-Roncero, M.; Rubio-Ruiz, B.; Saladino, G.; Conejo-Garcia, A.; Espinosa, A.; Velazquez-Campoy, A.; Gervasio, F.L.; Entrena, A.; Hurtado-Guerrero, R.
    The mechanism of allosteric coupling in choline kinase alpha1 revealed by the action of a rationally designed inhibitor (2013), Angew. Chem. Int. Ed. Engl., 52, 4582-4586.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.32 1-[4-(4-[4-[(6-amino-9H-purin-8-yl)methyl]phenyl]butyl)benzyl]-4-(dimethylamino)pyridinium bromide
-
 Helicobacter pylori
2.7.1.32 hemicholinium-3
-
 Helicobacter pylori

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.32 Mg2+ required Helicobacter pylori

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.32 Helicobacter pylori
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.32 ATP + choline
-
 Helicobacter pylori ADP + phosphocholine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.32 CHOKalpha1
-
 Helicobacter pylori
2.7.1.32 choline kinase alpha1
-
 Helicobacter pylori