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Literature summary extracted from

  • Palacios-Chaves, L.; Zuniga-Ripa, A.; Gutierrez, A.; Gil-Ramirez, Y.; Conde-Alvarez, R.; Moriyon, I.; Iriarte, M.
    Identification and functional analysis of the cyclopropane fatty acid synthase of Brucella abortus (2012), Microbiology, 158, 1037-1044.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.79 Brucella abortus
-
-
-
2.1.1.79 Brucella abortus 2308 NalR
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.79 S-adenosyl-L-methionine + phospholipid olefinic fatty acid
-
 Brucella abortus S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid
-
 ?
2.1.1.79 S-adenosyl-L-methionine + phospholipid olefinic fatty acid
-
 Brucella abortus 2308 NalR S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.79 CFA synthase
-
 Brucella abortus
2.1.1.79 cyclopropane fatty acid synthase
-
 Brucella abortus

Expression

EC Number Organism Comment Expression
2.1.1.79 Brucella abortus enzyme expression is promoted by acid pH and high osmolarity up

General Information

EC Number General Information Comment Organism
2.1.1.79 malfunction enzyme deficiency does not alter the ability of Brucella abortus to multiply in RAW 264.7 macrophages and in mice Brucella abortus
2.1.1.79 physiological function the enzyme is useful for survival extracellularly, thus facilitating persistence in contaminated materials and transmission to new hosts Brucella abortus