Literature summary extracted from
Choudhury, S.R.; Westfall, C.S.; Laborde, J.P.; Bisht, N.C.; Jez, J.M.; Pandey, S.
Two chimeric regulators of G-protein signaling (RGS) proteins differentially modulate soybean heterotrimeric G-protein cycle (2012), J. Biol. Chem., 287, 17870-17881.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
3.6.5.1 |
RGS1 protein |
G-protein signaling proteins, RGS proteins, accelerate the inherent GTPase activity of Galpha proteins. The GTPase-accelerating activities of GmRGS1 and -2 differ for each GmGalpha. Differential effects of GmRGS1 and GmRGS2 on GmGalpha1-4 result from a single valine versus alanine difference. GmRGS protein sequence comparisons and expression pattern, overview |
Glycine max |
|
3.6.5.1 |
RGS2 protein |
G-protein signaling proteins, RGS proteins, accelerate the inherent GTPase activity of Galpha proteins. The GTPase-accelerating activities of GmRGS1 and -2 differ for each GmGalpha. Differential effects of GmRGS1 and GmRGS2 on GmGalpha1-4 result from a single valine versus alanine difference. GmRGS protein sequence comparisons and expression pattern, overview |
Glycine max |
|
KM Value [mM]
EC Number |
KM Value [mM] |
KM Value Maximum [mM] |
Substrate |
Comment |
Organism |
Structure |
---|
3.6.5.1 |
additional information |
- |
additional information |
kinetics of 2'-/3'-O-N'-methylanthraniloyl-labeled GTP/GDP exchange for GmGalpha1-GmGalpha4, overview. GmGalpha1 and GmGalpha4 bind GTP more rapidly thanGmGalpha2 and GmGalpha3 |
Glycine max |
|
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
3.6.5.1 |
Mg2+ |
required |
Glycine max |
|
Natural Substrates/ Products (Substrates)
EC Number |
Natural Substrates |
Organism |
Comment (Nat. Sub.) |
Natural Products |
Comment (Nat. Pro.) |
Rev. |
Reac. |
---|
3.6.5.1 |
GTP + H2O |
Glycine max |
- |
GDP + phosphate |
- |
? |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
3.6.5.1 |
Glycine max |
- |
cv. Jack Seeds, four soybean Galpha proteins GmGalpha1-4 |
- |
Source Tissue
EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
---|
3.6.5.1 |
additional information |
expression patterns of GmGalpha1-4 are differentially regulated in different tissues of soybean and at various growth and development phases, e.g. during seed development and seed germination |
Glycine max |
- |
Substrates and Products (Substrate)
EC Number |
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
---|
3.6.5.1 |
GTP + H2O |
- |
Glycine max |
GDP + phosphate |
- |
? |
|
Subunits
EC Number |
Subunits |
Comment |
Organism |
---|
3.6.5.1 |
heterotrimer |
- |
Glycine max |
Synonyms
EC Number |
Synonyms |
Comment |
Organism |
---|
3.6.5.1 |
heterotrimeric G-protein |
- |
Glycine max |
Temperature Optimum [°C]
EC Number |
Temperature Optimum [°C] |
Temperature Optimum Maximum [°C] |
Comment |
Organism |
---|
3.6.5.1 |
20 |
25 |
assay at |
Glycine max |
pH Optimum
EC Number |
pH Optimum Minimum |
pH Optimum Maximum |
Comment |
Organism |
---|
3.6.5.1 |
8 |
- |
assay at |
Glycine max |
General Information
EC Number |
General Information |
Comment |
Organism |
---|
3.6.5.1 |
metabolism |
complex regulation of the G-protein cycle in soybean and in other plants with expanded G-protein networks |
Glycine max |
3.6.5.1 |
physiological function |
Galpha proteins regulate G-protein signaling working with RGS proteins |
Glycine max |