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Literature summary extracted from

  • Hallson, G.; Hollebakken, R.E.; Li, T.; Syrzycka, M.; Kim, I.; Cotsworth, S.; Fitzpatrick, K.A.; Sinclair, D.A.; Honda, B.M.
    dSet1 is the main H3K4 di- and tri-methyltransferase throughout Drosophila development (2012), Genetics, 190, 91-100.
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.354 Drosophila melanogaster
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.354 larva
-
 Drosophila melanogaster
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.354 S-adenosyl-L-methionine + histone H3(K4)
-
 Drosophila melanogaster ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.354 dSet1
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 Drosophila melanogaster
2.1.1.354 H3K4 HMT
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 Drosophila melanogaster
2.1.1.354 H3K4 methyltransferase
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 Drosophila melanogaster

General Information

EC Number General Information Comment Organism
2.1.1.354 malfunction histone H3(K4) di- and trimethylations are significantly reduced in dSet1 mutants during late larval und post-larval stages Drosophila melanogaster
2.1.1.354 physiological function dSet1 is the main histone H3(K4) di- and tri-methyltransferase throughout Drosophila development. dSet1 interacts with members of a putative Drosophila COMPASS (complex of proteins associated with Set1) which is functionally required for histone H3(K4) methylation Drosophila melanogaster