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Literature summary extracted from

  • Long, K.S.; Munck, C.; Andersen, T.M.; Schaub, M.A.; Hobbie, S.N.; Boettger, E.C.; Vester, B.
    Mutations in 23S rRNA at the peptidyl transferase center and their relationship to linezolid binding and cross-resistance (2010), Antimicrob. Agents Chemother., 54, 4705-4713.
    View publication on PubMedView publication on EuropePMC

Protein Variants

EC Number Protein Variants Comment Organism
2.3.2.12 additional information single mutations at positions 2032, 2453, and 2499 to human cytosolic base identity do not confer significantly reduced susceptibility to linezolid. The largest decrease in linezolid susceptibility is observed with the G2576U mutation Mycolicibacterium smegmatis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.2.12 ribosome
-
 Mycolicibacterium smegmatis 5840
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.12 Mycolicibacterium smegmatis
-
-
-
2.3.2.12 Mycolicibacterium smegmatis SZ558
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.3.2.12 PTC
-
 Mycolicibacterium smegmatis