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Literature summary extracted from

  • Kerscher, S.; Okun, J.; Brandt, U.
    A single external enzyme confers alternative NADH:ubiquinone oxidoreductase activity in Yarrowia lipolytica (1999), J. Cell Sci., 112, 2347-2354.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.6.5.9 additional information not inhibited by piericidin A. Addition of up to 10% (v/v) ethanol has no effect on NADH:NBQ oxidoreductase activity Yarrowia lipolytica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.6.5.9 0.014
-
 NADH pH and temperature not specified in the publication Yarrowia lipolytica

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.6.5.9 mitochondrial membrane NDH2 is oriented towards the external face of the mitochondrial inner membrane Yarrowia lipolytica 31966
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.6.5.9 65800
-
 calculated from amino acid sequence Yarrowia lipolytica

Organism

EC Number Organism UniProt Comment Textmining
1.6.5.9 Yarrowia lipolytica
-
-
-
1.6.5.9 Yarrowia lipolytica E 150
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.6.5.9 additional information alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane Yarrowia lipolytica ?
-
 ?
1.6.5.9 additional information alternative NADH:ubiquinone oxidoreductase does not pump protons across the inner mitochondrial membrane Yarrowia lipolytica E 150 ?
-
 ?
1.6.5.9 NADH + H+ + 5-nonylubiquinone
-
 Yarrowia lipolytica NAD+ + 5-nonylubiquinol
-
 ?
1.6.5.9 NADH + H+ + 5-nonylubiquinone
-
 Yarrowia lipolytica E 150 NAD+ + 5-nonylubiquinol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.6.5.9 alternative NADH:ubiquinone oxidoreductase
-
 Yarrowia lipolytica
1.6.5.9 external NADH:ubiquinone oxidoreductase
-
 Yarrowia lipolytica
1.6.5.9 NDH2
-
 Yarrowia lipolytica

Cofactor

EC Number Cofactor Comment Organism Structure
1.6.5.9 NADH
-
 Yarrowia lipolytica

General Information

EC Number General Information Comment Organism
1.6.5.9 malfunction strains carrying the deletion of NDH2 are completely viable Yarrowia lipolytica