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Literature summary extracted from

  • Sienkiewicz-Porzucek, A.; Sulpice, R.; Osorio, S.; Krahnert, I.; Leisse, A.; Urbanczyk-Wochniak, E.; Hodges, M.; Fernie, A.R.; Nunes-Nesi, A.
    Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth (2010), Mol. Plant, 3, 156-173.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.41 gene SlIDH1, DNA and amino acid sequence determination and analysis, phylogenetic analysis, expression in antisense orientation in tomato plants Solanum lycopersicum

Protein Variants

EC Number Protein Variants Comment Organism
1.1.1.41 additional information transgenic tomato plants expressing the IDH gene in antisense orientation display a mild reduction in the activity of the target enzyme in the leaves but essentially no visible alteration in growth from the wild-type. Fruit size and yield are, however, reduced Solanum lycopersicum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.41 mitochondrion
-
 Solanum lycopersicum 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.41 isocitrate + NAD+ Solanum lycopersicum
-
 2-oxoglutarate + NADH + H+ + CO2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.41 Solanum lycopersicum
-
 gene SlIDH1
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.41 leaf
-
 Solanum lycopersicum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.41 isocitrate + NAD+
-
 Solanum lycopersicum 2-oxoglutarate + NADH + H+ + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.41 IDH1
-
 Solanum lycopersicum
1.1.1.41 mIDH
-
 Solanum lycopersicum
1.1.1.41 mitochondrial NAD-dependent isocitrate dehydrogenase
-
 Solanum lycopersicum
1.1.1.41 NAD-Dependent IDH
-
 Solanum lycopersicum

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.41 NAD+
-
 Solanum lycopersicum

General Information

EC Number General Information Comment Organism
1.1.1.41 additional information reduction of mitochondrial IDH activity has little effect on the relative electron transport or assimilation rates and a minor reduction in the maximum efficiency of PSII Solanum lycopersicum