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Literature summary extracted from

  • Arnesen, T.; Gromyko, D.; Kagabo, D.; Betts, M.; Starheim, K.; Varhaug, J.; Anderson, D.; Lillehaug, J.
    A novel human NatA Nα-terminal acetyltransferase complex: HNaa16p-hNaa10p (hNat2-hArd1) (2009), BMC Biochem., 10, 15.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.255 a plasmid expressing hNaa16p, NARG1L-FLAG, is used Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.255 siRNA
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.255 ribosome
-
 Homo sapiens 5840
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.255 acetyl-CoA + peptide Homo sapiens
-
 Nalpha-acetylpeptide + CoA
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.255 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.255 ribosomes of HEK-293 cells are isolated Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.255 8305C cell
-
 Homo sapiens
-
2.3.1.255 A-431 cell
-
 Homo sapiens
-
2.3.1.255 ARO cell
-
 Homo sapiens
-
2.3.1.255 B-CPAP cell
-
 Homo sapiens
-
2.3.1.255 BHT-101 cell
-
 Homo sapiens
-
2.3.1.255 CAL-62 cell
-
 Homo sapiens
-
2.3.1.255 CGTH-W1 cell
-
 Homo sapiens
-
2.3.1.255 GaMG cell
-
 Homo sapiens
-
2.3.1.255 HCT-116 cell
-
 Homo sapiens
-
2.3.1.255 HEK-293 cell
-
 Homo sapiens
-
2.3.1.255 HeLa cell
-
 Homo sapiens
-
2.3.1.255 Hep-G2 cell
-
 Homo sapiens
-
2.3.1.255 MCF-7 cell
-
 Homo sapiens
-
2.3.1.255 NCI-H1299 cell
-
 Homo sapiens
-
2.3.1.255 NPA cell
-
 Homo sapiens
-
2.3.1.255 Nthy-ori 3-1 cell
-
 Homo sapiens
-
2.3.1.255 ONCO-DG1 cell
-
 Homo sapiens
-
2.3.1.255 SK-MEL-2 cell
-
 Homo sapiens
-
2.3.1.255 SK-N-MC cell
-
 Homo sapiens
-
2.3.1.255 TAD-2 cell
-
 Homo sapiens
-
2.3.1.255 thyroid gland
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.255 acetyl-CoA + peptide
-
 Homo sapiens Nalpha-acetylpeptide + CoA
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.255 hNaa16p
-
 Homo sapiens
2.3.1.255 hNat2
-
 Homo sapiens
2.3.1.255 NatA Nalpha-terminal acetyltransferase
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.255 37
-
 acetylation assay Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.255 8.5
-
 acetylation assay Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.255 acetyl-CoA
-
 Homo sapiens