EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.17 | Al3+ | modulation of AGODH activity, exposure of the Al-challenged cells to a control medium results in a dramatic decrease in the activity of AGODH, in contrast, control cells incubated in an Al-enriched medium display an intense activity band, AGODH may be pivotal to the adaptation of Pseudomonas fluorescens to aluminium toxicity | Pseudomonas fluorescens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.17 | glyoxylate + CoA + NADP+ | Pseudomonas fluorescens | - |
oxalyl-CoA + NADPH + H+ | - |
r | |
1.2.1.17 | additional information | Pseudomonas fluorescens | modified TCA cycle with diminished efficacy in NADH production and decreased CO2-evolving capacity, orchestrates the synthesis of oxalate, NADPH and ATP, ingredients pivotal to the survival in an aluminium environment | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.1.17 | Pseudomonas fluorescens | - |
- |
- |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.2.1.17 | additional information | - |
upregulation of acylating glyoxylate dehydrogenase leads to an enhanced synthesis of oxalate, a dicarboxylic acid involved in the immobilization of aluminum, exposure of the Al-challenged cells to a control medium results in a dramatic decrease in the activity of AGODH, in contrast, control cells incubated in an Al-enriched medium display an intense activity band | Pseudomonas fluorescens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.1.17 | glyoxylate + CoA + NADP+ | - |
Pseudomonas fluorescens | oxalyl-CoA + NADPH + H+ | - |
r | |
1.2.1.17 | additional information | modified TCA cycle with diminished efficacy in NADH production and decreased CO2-evolving capacity, orchestrates the synthesis of oxalate, NADPH and ATP, ingredients pivotal to the survival in an aluminium environment | Pseudomonas fluorescens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.2.1.17 | acylating glyoxylate dehydrogenase | - |
Pseudomonas fluorescens |
1.2.1.17 | AGODH | - |
Pseudomonas fluorescens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.2.1.17 | NADP+ | - |
Pseudomonas fluorescens |