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Literature summary extracted from

  • Schmidt, I.
    Nitric oxide: interaction with the ammonia monooxygenase and regulation of metabolic activities in ammonia oxidizers (2008), Methods Enzymol., 440, 121-135.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.99.39 ammonia + AH2 + O2 Nitrosomonas europaea anaerobic ammonia oxidation NH2OH + A + H2O
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Organism

EC Number Organism UniProt Comment Textmining
1.14.99.39 Nitrosomonas europaea
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.39 ammonia + AH2 + O2 anaerobic ammonia oxidation Nitrosomonas europaea NH2OH + A + H2O
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1.14.99.39 ammonia + AH2 + O2 under both oxic and anoxic conditions, the enzyme is responsible for the oxidation of ammonia to hydroxylamine. NO and NO2 are assumed to act as additional oxidants Nitrosomonas europaea NH2OH + A + H2O
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1.14.99.39 additional information the affinity of the enzyme for NO2/N2O is higher than for O2. NO2 might be a suitable oxidant for aerobic ammonia oxidation as well Nitrosomonas europaea ?
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Synonyms

EC Number Synonyms Comment Organism
1.14.99.39 AMO
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Nitrosomonas europaea

Expression

EC Number Organism Comment Expression
1.14.99.39 Nitrosomonas europaea when Nitrosomonas cells are grown with pyruvate as the electron donor and nitrite as the electron acceptor under anoxic conditions, the amount of ammonia monooxygenase in the cells decreases. After about 2 weeks, ammonia monooxygenase is no longer detectable in the denitrifying cells down