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Literature summary extracted from

  • Wang, Z.; Zhou, W.
    Synthesis and in vitro antibacterial activity of (2S)-N-(substitutedphenyl)-1-[(2R)-2-[(formylhydroxyamino)methyl]-1-oxohexyl]-2-pyrrolidinecarboxamides as potential peptide deformylase inhibitors (2009), Chem. Biol. Drug Des., 73, 142-146.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.5.1.88 medicine the gene encoding peptide deformylase is present in all sequenced pathogenic bacterial genomes, therefore peptide deformylase is an attractive target for antibacterial chemotherapy Staphylococcus aureus
3.5.1.88 medicine the gene encoding peptide deformylase is present in all sequenced pathogenic bacterial genomes, therefore peptide deformylase is an attractive target for antibacterial chemotherapy Streptococcus pneumoniae
3.5.1.88 medicine the gene encoding peptide deformylase is present in all sequenced pathogenic bacterial genomes, therefore peptide deformylase is an attractive target for antibacterial chemotherapy Staphylococcus epidermidis
3.5.1.88 medicine the gene encoding peptide deformylase is present in all sequenced pathogenic bacterial genomes, therefore peptide deformylase is an attractive target for antibacterial chemotherapy Staphylococcus enteridis
3.5.1.88 medicine the gene encoding peptide deformylase is present in all sequenced pathogenic bacterial genomes, therefore peptide deformylase is an attractive target for antibacterial chemotherapy Staphylococcus non-hemolyticus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 BB-83698
-
 Staphylococcus aureus
3.5.1.88 BB-83698
-
 Staphylococcus enteridis
3.5.1.88 BB-83698
-
 Staphylococcus epidermidis
3.5.1.88 BB-83698
-
 Staphylococcus non-hemolyticus
3.5.1.88 BB-83698
-
 Streptococcus pneumoniae
3.5.1.88 LBM-415
-
 Staphylococcus aureus
3.5.1.88 LBM-415
-
 Staphylococcus enteridis
3.5.1.88 LBM-415
-
 Staphylococcus epidermidis
3.5.1.88 LBM-415
-
 Staphylococcus non-hemolyticus
3.5.1.88 LBM-415
-
 Streptococcus pneumoniae
3.5.1.88 N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus aureus
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus enteridis
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus epidermidis
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Staphylococcus non-hemolyticus
3.5.1.88 N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
-
 Streptococcus pneumoniae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.5.1.88 Fe2+
-
 Staphylococcus aureus
3.5.1.88 Fe2+
-
 Streptococcus pneumoniae
3.5.1.88 Fe2+
-
 Staphylococcus epidermidis
3.5.1.88 Fe2+
-
 Staphylococcus enteridis
3.5.1.88 Fe2+
-
 Staphylococcus non-hemolyticus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.1.88 additional information Staphylococcus aureus peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis ?
-
 ?
3.5.1.88 additional information Streptococcus pneumoniae peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis ?
-
 ?
3.5.1.88 additional information Staphylococcus epidermidis peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis ?
-
 ?
3.5.1.88 additional information Staphylococcus enteridis peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis ?
-
 ?
3.5.1.88 additional information Staphylococcus non-hemolyticus peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.1.88 Staphylococcus aureus
-
-
-
3.5.1.88 Staphylococcus enteridis
-
-
-
3.5.1.88 Staphylococcus epidermidis
-
-
-
3.5.1.88 Staphylococcus non-hemolyticus
-
-
-
3.5.1.88 Streptococcus pneumoniae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.1.88 additional information peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis Staphylococcus aureus ?
-
 ?
3.5.1.88 additional information peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis Streptococcus pneumoniae ?
-
 ?
3.5.1.88 additional information peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis Staphylococcus epidermidis ?
-
 ?
3.5.1.88 additional information peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis Staphylococcus enteridis ?
-
 ?
3.5.1.88 additional information peptide deformylase is responsible for the removal of the N-formyl group from the terminal methionine residue in bacterial protein synthesis Staphylococcus non-hemolyticus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.1.88 peptide deformylase
-
 Staphylococcus aureus
3.5.1.88 peptide deformylase
-
 Streptococcus pneumoniae
3.5.1.88 peptide deformylase
-
 Staphylococcus epidermidis
3.5.1.88 peptide deformylase
-
 Staphylococcus enteridis
3.5.1.88 peptide deformylase
-
 Staphylococcus non-hemolyticus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Streptococcus pneumoniae N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.049 microg/ml Staphylococcus enteridis N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.098 microg/ml Streptococcus pneumoniae N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae LBM-415
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus enteridis N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus aureus N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus aureus N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus enteridis N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus non-hemolyticus N-(3-chloro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus enteridis N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Staphylococcus epidermidis N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.195 microg/ml Streptococcus pneumoniae N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus LBM-415
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis LBM-415
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(1H-pyrrol-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus enteridis N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus enteridis N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Streptococcus pneumoniae N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus aureus N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus non-hemolyticus N-[3-fluoro-4-(1H-pyrrol-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Streptococcus pneumoniae N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Streptococcus pneumoniae N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.39 microg/ml Staphylococcus epidermidis N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus non-hemolyticus LBM-415
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Streptococcus pneumoniae N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus aureus N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus epidermidis N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 0.78 microg/ml Staphylococcus epidermidis N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus non-hemolyticus N-(3-fluoro-4-pyrrolidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus epidermidis N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus non-hemolyticus N-[3-fluoro-4-(4-methyl-1,4-diazepan-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus epidermidis N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus aureus N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 1.56 microg/ml Staphylococcus enteridis N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus enteridis LBM-415
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(3-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-morpholin-4-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-piperidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-pyrrolidin-1-ylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-methylpiperazin-1-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Streptococcus pneumoniae 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-(3-chloro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus enteridis N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-(3-fluoro-4-piperidin-1-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-(4-chlorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus aureus N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus epidermidis N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-[3-chloro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus aureus N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-[3-fluoro-4-(1-oxidopiperidin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus aureus N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus non-hemolyticus N-[4-(4-ethylpiperazin-1-yl)-3-fluorophenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus aureus N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 3.13 microg/ml Staphylococcus enteridis N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 6.25 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 6.25 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(4-methoxyphenyl)-L-prolinamide
3.5.1.88 additional information
-
 6.25 microg/ml Staphylococcus non-hemolyticus N-(3,4-difluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 6.25 microg/ml Staphylococcus non-hemolyticus N-[4-(4-ethylpiperazin-1-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-(2-methylphenyl)-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus aureus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus epidermidis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus enteridis 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus 1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-N-[4-(4-oxidomorpholin-4-yl)phenyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus N-(3-chloro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus N-(3-fluoro-4-morpholin-4-ylphenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus N-(4-fluorophenyl)-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide
3.5.1.88 additional information
-
 larger than 6.25 microg/ml Staphylococcus non-hemolyticus N-[3-fluoro-4-(4-oxidomorpholin-4-yl)phenyl]-1-[(2R)-2-[[formyl(hydroxy)amino]methyl]hexanoyl]-L-prolinamide