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Literature summary extracted from

  • Zhang, X.; Newman, E.
    Deficiency in L-serine deaminase results in abnormal growth and cell division of Escherichia coli K-12 (2008), Mol. Microbiol., 69, 870-881.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
4.3.1.17 additional information construction of a mutant strain devoid of functional genes sdaA, sdaB, tdcG encoding the three isozymes of the organism, the loss of the ability to deaminate L-serine severely impairs growth and cell division in Escherichia coli K-12 leading e.g. to filamentation, phenotype, overview Escherichia coli K-12

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.3.1.17 L-serine Escherichia coli K-12
-
 pyruvate + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.3.1.17 Escherichia coli K-12
-
 three genes sdaA, sdaB, tdcG encoding the isozymes of SDH
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.3.1.17 L-serine
-
 Escherichia coli K-12 pyruvate + NH3
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.3.1.17 L-SD
-
 Escherichia coli K-12

Cofactor

EC Number Cofactor Comment Organism Structure
4.3.1.17 pyridoxal 5'-phosphate dependent on Escherichia coli K-12