EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.222 | additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Drosophila melanogaster | |
2.4.1.222 | additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Mammalia | |
2.4.1.222 | additional information | fringe requires a properly folded EGF repeat modified by O-fucose for its enzymatic activity | Homo sapiens |
EC Number | Application | Comment | Organism |
---|---|---|---|
2.4.1.222 | medicine | the Notch signaling pathway is involved in numerous developmental cascades in mammals, mutations in the pathway have been implicated in a variety of Human diseases, like CADASIL, spondylocostal dysostosis, alagille syndrome, cancer and multiple sclerosis | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.4.1.222 | - |
Mammalia |
EC Number | Crystallization (Comment) | Organism |
---|---|---|
2.4.1.222 | - |
Mammalia |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.1.222 | Golgi apparatus | - |
Drosophila melanogaster | 5794 | - |
2.4.1.222 | Golgi apparatus | - |
Mammalia | 5794 | - |
2.4.1.222 | Golgi apparatus | - |
Homo sapiens | 5794 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.222 | Mn2+ | - |
Drosophila melanogaster | |
2.4.1.222 | Mn2+ | - |
Mammalia | |
2.4.1.222 | Mn2+ | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.222 | additional information | Drosophila melanogaster | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? | |
2.4.1.222 | additional information | Mammalia | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? | |
2.4.1.222 | additional information | Homo sapiens | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.222 | Drosophila melanogaster | - |
- |
- |
2.4.1.222 | Homo sapiens | - |
- |
- |
2.4.1.222 | Mammalia | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.4.1.222 | - |
Mammalia |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.222 | eye | - |
Drosophila melanogaster | - |
2.4.1.222 | leg | - |
Drosophila melanogaster | - |
2.4.1.222 | oocyte | - |
Drosophila melanogaster | - |
2.4.1.222 | wing | - |
Drosophila melanogaster | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.222 | additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Drosophila melanogaster | ? | - |
? | |
2.4.1.222 | additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Mammalia | ? | - |
? | |
2.4.1.222 | additional information | transfers a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.222 | beta-1,3-N-acetylglucosaminyltransferase | - |
Drosophila melanogaster |
2.4.1.222 | beta-1,3-N-acetylglucosaminyltransferase | - |
Mammalia |
2.4.1.222 | beta-1,3-N-acetylglucosaminyltransferase | - |
Homo sapiens |
2.4.1.222 | Dfng | - |
Drosophila melanogaster |