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Literature summary extracted from

  • Antosova, M.; Strapkova, A.; Turcan, T.
    Exogenous irritant-induced airway hyperreactivity and inhibition of soluble guanylyl cyclase (2008), Biol. Res. Nurs., 10, 93-101.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.6.1.2 NO
-
 Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.6.1.2 methylene blue a nonspecific sGC inhibitor Cavia porcellus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.6.1.2 soluble
-
 Cavia porcellus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.6.1.2 GTP Cavia porcellus mechanism of NO stimulation of cGMP production in airway hyperreactivity pathogenesis evoked by toluene inhalation, overview 3',5'-cyclic GMP + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.6.1.2 Cavia porcellus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.6.1.2 lung
-
 Cavia porcellus
-
4.6.1.2 respiratory tract
-
 Cavia porcellus
-
4.6.1.2 smooth muscle tracheal and lung tissue smooth muscle Cavia porcellus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.6.1.2 GTP
-
 Cavia porcellus 3',5'-cyclic GMP + diphosphate
-
 ?
4.6.1.2 GTP mechanism of NO stimulation of cGMP production in airway hyperreactivity pathogenesis evoked by toluene inhalation, overview Cavia porcellus 3',5'-cyclic GMP + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.6.1.2 sGC
-
 Cavia porcellus
4.6.1.2 soluble guanylyl cyclase
-
 Cavia porcellus