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Literature summary extracted from

  • Kragh, P.M.; Pedersen, C.B.; Schmidt, S.P.; Winter, V.S.; Vajta, G.; Gregersen, N.; Bolund, L.; Corydon, T.J.
    Handling of human short-chain acyl-CoA dehydrogenase (SCAD) variant proteins in transgenic mice (2007), Mol. Genet. Metab., 91, 128-137.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.3.8.1 expressed in Mus musculus Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.3.8.1 G185S the mutant is not detected at protein level but shows high mRNA levels Homo sapiens
1.3.8.1 R83C unable to form tetramers, soluble mutant enzyme is not detected at steady-state Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.1 mitochondrion
-
 Homo sapiens 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.1 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.1 brain wild type enzyme expression at protein level is only detected in brain Homo sapiens
-
1.3.8.1 liver
-
 Homo sapiens
-
1.3.8.1 muscle
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.1 butyryl-CoA + electron acceptor
-
 Homo sapiens 2-butenoyl-CoA + reduced acceptor
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.3.8.1 SCAD
-
 Homo sapiens
1.3.8.1 short-chain acyl-CoA dehydrogenase
-
 Homo sapiens