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Literature summary extracted from

  • Plant, A.; Thompson, P.; Williams, D.M.
    Stereoselective synthesis of novel uracil polyoxin C conjugates as substrate analogues of chitin synthase (2008), J. Org. Chem., 73, 3714-3724.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.4.1.16 agriculture enzyme inhibitors can be useful as potential pesticidal agents Saccharomyces cerevisiae
2.4.1.16 agriculture enzyme inhibitors can be useful as potential pesticidal agents Candida albicans

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.16 nikkomycin Z
-
 Candida albicans
2.4.1.16 nikkomycin Z
-
 Saccharomyces cerevisiae
2.4.1.16 Polyoxin D
-
 Candida albicans
2.4.1.16 Polyoxin D
-
 Saccharomyces cerevisiae
2.4.1.16 polyoxin L
-
 Candida albicans
2.4.1.16 polyoxin L
-
 Saccharomyces cerevisiae
2.4.1.16 uracil polyoxin C methyl ester stereoselective synthesis routes of both the natural (C5'-S) and unnatural (C5'-R) diastereoisomers of uracil polyoxin C methyl ester as specific substrate analogue-inhibitors of chirin synthase, conjugation of the methyl ester of uracil polyoxin C with activated isoxazole carboxylic acids, detailed overview Candida albicans
2.4.1.16 uracil polyoxin C methyl ester stereoselective synthesis routes of both the natural (C5'-S) and unnatural (C5'-R) diastereoisomers of uracil polyoxin C methyl ester as specific substrate analogue-inhibitors of chirin synthase, conjugation of the methyl ester of uracil polyoxin C with activated isoxazole carboxylic acids, detailed overview Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Candida albicans
-
-
-
2.4.1.16 Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-D-glucosamine + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n
-
 Saccharomyces cerevisiae UDP + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n+1
-
 ?
2.4.1.16 UDP-N-acetyl-D-glucosamine + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n
-
 Candida albicans UDP + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n+1
-
 ?