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Literature summary extracted from

  • Hiltunen, J.K.; Palosaari, P.M.; Kunau, W.H.
    Epimerization of 3-hydroxyacyl-CoA esters in rat liver. Involvement of two 2-enoyl-CoA hydratases (1989), J. Biol. Chem., 264, 13536-13540.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.1.119 NEM 60% inhibition by 5 mM, 96% inhibition by 10 mM NEM Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.2.1.17 Rattus norvegicus
-
-
-
4.2.1.119 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.2.1.17 liver
-
 Rattus norvegicus
-
4.2.1.119 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.1.17 crotonyl-CoA + H2O ratio of hydration rates trans-2-decenoyl-CoA/crotonyl-CoA is 0.29 Rattus norvegicus (3S)-3-hydroxybutanoyl-CoA
-
 r
4.2.1.17 trans-2-decenoyl-CoA + H2O ratio of hydration rates trans-2-decenoyl-CoA/crotonyl-CoA is 0.29 Rattus norvegicus (3S)-hydroxydecanoyl-CoA
-
 r
4.2.1.119 Crotonyl-CoA + H2O ratio of hydration rates trans-2-decenoyl-CoA/crotonyl-CoA is 14.4 Rattus norvegicus (3R)-3-Hydroxybutanoyl-CoA
-
 r
4.2.1.119 trans-2-decenoyl-CoA + H2O ratio of hydration rates trans-2-decenoyl-CoA/crotonyl-CoA is 14.4 Rattus norvegicus (3R)-hydroxydecanoyl-CoA
-
 r

Synonyms

EC Number Synonyms Comment Organism
4.2.1.17 2-enoyl-hydratase 1
-
 Rattus norvegicus
4.2.1.17 classic 2-enoyl-CoA hydratase
-
 Rattus norvegicus
4.2.1.119 2-enoyl-CoA hydratase
-
 Rattus norvegicus
4.2.1.119 2-enoyl-CoA hydratase 2
-
 Rattus norvegicus
4.2.1.119 2-enoyl-hydratase 2
-
 Rattus norvegicus