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Literature summary extracted from

  • Roca, I.; Ballana, E.; Panosa, A.; Torrents, E.; Gibert, I.
    Fumarate and nitrate reduction (FNR) dependent activation of the Escherichia coli anaerobic ribonucleotide reductase nrdDG promoter (2008), Int. Microbiol., 11, 49-56.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.17.4.2 the nrdDG promoter regulates transcriptional expression of the anaerobic ribonucleotide reductase of Escherichia coli, binding of the pleiotropic FNR, fumarate and nitrate reduction, transcriptional regulator to the nrdDG promoter region affects the transcription, the upstream FNR-2 site is essential for anaerobic activation of the nrdDG promoter. Although the FNR-1 site is not absolutely required, it allows maximal expression of this promoter, overview Escherichia coli K-12

Protein Variants

EC Number Protein Variants Comment Organism
1.17.4.2 additional information fnr and arcA mutant strains are constructed by introducing the indicated mutation into strain IG40 by P1 transduction followed by selection for the appropriate drug resistance Escherichia coli K-12

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.4.2 additional information Escherichia coli K-12 the anaerobic ribonucleotide reductase of Escherichia coli is an essential enzyme required to supply the building blocks for DNA synthesis ?
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Organism

EC Number Organism UniProt Comment Textmining
1.17.4.2 Escherichia coli K-12
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.4.2 additional information the anaerobic ribonucleotide reductase of Escherichia coli is an essential enzyme required to supply the building blocks for DNA synthesis Escherichia coli K-12 ?
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 ?