EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.3.1 | 5-Androstene-3,17-dione | Pseudomonas sp. | - |
4-Androstene-3,17-dione | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.3.1 | Pseudomonas sp. | - |
- |
- |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
5.3.3.1 | a 3-oxo-DELTA5-steroid = a 3-oxo-DELTA4-steroid | two-step reaction first, Asp38 acts as a base, abstracting the 4beta-H atom from C-4 of the steroid to form a dienolate as the intermediate, next, the intermediate is reketonized by proton transfer to the 6beta-position, each step goes through its own transition state, catalytic mechanism, theoretical model involving residues Tyr14, Asp38 and Asp99 | Pseudomonas sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.3.1 | 5-Androstene-3,17-dione | - |
Pseudomonas sp. | 4-Androstene-3,17-dione | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.3.1 | DELTA5-3-ketosteroid isomerase | - |
Pseudomonas sp. |
5.3.3.1 | KSI | - |
Pseudomonas sp. |