Literature summary extracted from

Zhang, M.; Yang, Y.; Xu, Y.; Qie, Y.; Wang, J.; Zhu, B.; Wang, Q.; Jin, R.; Xu, S.; Wang, H.
Trehalose-6-phosphate phosphatase from Mycobacterium tuberculosis induces humoral and cellular immune responses (2007), FEMS Immunol. Med. Microbiol., 49, 68-74.

Application

EC Number	Application	Comment	Organism
3.1.3.12	medicine	may be a candidate for vaccine development for the control of tuberculosis	Mycobacterium tuberculosis
3.1.3.12	medicine	may be a candidate for vaccine development for the control of tuberculosis	Mycobacterium tuberculosis variant bovis

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.1.3.12	expressed in Escherichia coli BL21(DE3) cells	Mycobacterium tuberculosis

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.3.12	cell wall	-	Mycobacterium tuberculosis	5618	-
3.1.3.12	cell wall	-	Mycobacterium tuberculosis variant bovis	5618	-
3.1.3.12	membrane	-	Mycobacterium tuberculosis	16020	-
3.1.3.12	membrane	-	Mycobacterium tuberculosis variant bovis	16020	-

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.1.3.12	42000	-	SDS-PAGE	Mycobacterium tuberculosis
3.1.3.12	42000	-	SDS-PAGE	Mycobacterium tuberculosis variant bovis

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.12	Mycobacterium tuberculosis	-	-	-
3.1.3.12	Mycobacterium tuberculosis H37Rv	-	-	-
3.1.3.12	Mycobacterium tuberculosis variant bovis	-	-	-
3.1.3.12	Mycobacterium tuberculosis variant bovis Calmette-Guerin	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.1.3.12	Ni-NTA affinity chromatography	Mycobacterium tuberculosis

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.12	trehalose 6-phosphate + H2O	-	Mycobacterium tuberculosis	trehalose + phosphate	-	?
3.1.3.12	trehalose 6-phosphate + H2O	-	Mycobacterium tuberculosis variant bovis	trehalose + phosphate	-	?
3.1.3.12	trehalose 6-phosphate + H2O	-	Mycobacterium tuberculosis H37Rv	trehalose + phosphate	-	?
3.1.3.12	trehalose 6-phosphate + H2O	-	Mycobacterium tuberculosis variant bovis Calmette-Guerin	trehalose + phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
3.1.3.12	TPP	-	Mycobacterium tuberculosis
3.1.3.12	TPP	-	Mycobacterium tuberculosis variant bovis
3.1.3.12	trehalose-6-phosphate phosphatase	-	Mycobacterium tuberculosis
3.1.3.12	trehalose-6-phosphate phosphatase	-	Mycobacterium tuberculosis variant bovis

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Release 2023.1 (January 2023)