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Literature summary extracted from

  • Brobey, R.K.; Soong, L.
    Leishmania species: evidence for transglutaminase activity and its role in parasite proliferation (2006), Exp. Parasitol., 114, 94-102.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 cystamine
-
 Leishmania amazonensis
2.3.2.13 iodoacetamide
-
 Leishmania amazonensis
2.3.2.13 Monodansylcadaverine
-
 Leishmania amazonensis
2.3.2.13 additional information not inhibitory: didansylcadaverine Leishmania amazonensis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 additional information enzyme is dependent on Ca2+ Leishmania amazonensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 leishmanolysin + alkylamine Leishmania amazonensis
-
 ?
-
 ?
2.3.2.13 additional information Leishmania amazonensis major substrates of enzyme are in the range of 50-75 kDA ?
-
 ?
2.3.2.13 myo-inositol-1-phosphate synthase + alkylamine Leishmania amazonensis
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Leishmania amazonensis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 amastigote comparable activity in both promastigote and amastigote Leishmania amazonensis
-
2.3.2.13 promastigote comparable activity in both promastigote and amastigote Leishmania amazonensis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 leishmanolysin + alkylamine
-
 Leishmania amazonensis ?
-
 ?
2.3.2.13 additional information major substrates of enzyme are in the range of 50-75 kDA Leishmania amazonensis ?
-
 ?
2.3.2.13 myo-inositol-1-phosphate synthase + alkylamine
-
 Leishmania amazonensis ?
-
 ?